For research purposes only
KPV
KPV (Lys-Pro-Val, CAS 67727-97-3) is the three-residue C-terminal sequence of alpha-melanocyte-stimulating hormone that concentrates the peptide's melanocortin receptor-independent anti-inflammatory activity in the smallest possible pharmacophore. Intestinal epithelial and macrophage culture studies demonstrate that KPV blocks NF-kB nuclear translocation and attenuates pro-inflammatory cytokine output through a route that bypasses the MC1R pigmentation signaling pathway active in full-length alpha-MSH. This receptor-pathway separation makes KPV a clean probe for studying innate immune signaling in gut epithelial model systems. Supplied lyophilized for in vitro research use only.
Select size
$40.00
Specifications
- CAS
- 67727-97-3
- MW
- 342.43 g/mol
- Formula
- C16H30N4O4
- Purity
- >=99.4 HPLC
- Storage
- -20 °C, lyophilized
Research Notes
What is KPV?
KPV is a synthetic research compound studied in laboratory settings. It has molecular formula C16H30N4O4, a molecular weight of 342.43 g/mol, CAS 67727-97-3. It is intended for in vitro research use only and is not for human or animal use.
What purity is AminoLine's KPV?
AminoLine supplies KPV at >=99.4% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is KPV supplied?
KPV is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.