For research purposes only
MOTS-c
MOTS-c is a 16-amino acid open reading frame product of the mitochondrial 12S rRNA gene, making it the founding member of the mitochondrial-derived peptide (MDP) class with documented systemic metabolic signaling activity. In skeletal muscle and adipocyte culture models it activates AMPK and upregulates FGF21 expression, leading to increases in insulin-independent glucose uptake — a pattern consistent with mitochondria acting as endocrine-like signaling organelles. The non-nuclear genomic origin of MOTS-c gives it a distinct research value for investigating retrograde mito-nuclear communication and understanding how mitochondrial status is communicated to metabolic effector pathways. For laboratory research use only.
Select size
$60.00
Specifications
- CAS
- 1627580-64-6
- MW
- 2174.59 g/mol
- Formula
- C100H152N28O22S2
- Purity
- >=99.3 HPLC
- Storage
- -20 °C, lyophilized
Research Notes
What is MOTS-c?
MOTS-c is a synthetic research compound studied in laboratory settings. It has molecular formula C100H152N28O22S2, a molecular weight of 2174.59 g/mol, CAS 1627580-64-6. It is intended for in vitro research use only and is not for human or animal use.
What purity is AminoLine's MOTS-c?
AminoLine supplies MOTS-c at >=99.3% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is MOTS-c supplied?
MOTS-c is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.