For research purposes only
TB500
TB500 is a 43-amino acid synthetic peptide representing the principal bioactive region of Thymosin Beta-4 (TB4). Its conserved LKKTET actin-binding motif binds monomeric G-actin with high affinity, sequestering the unpolymerized pool and thereby shifting the G-actin/F-actin equilibrium toward depolymerization in cell culture systems. Researchers apply TB500 in endothelial and fibroblast models to study how actin dynamics feed into downstream biology — including integrin-dependent signaling, directional cell migration, and the cytoskeletal remodeling events underlying wound-biology pathways. For laboratory research use only.
Select size
$60.00
Specifications
- CAS
- 885340-08-9
- MW
- 868.99 g/mol
- Formula
- C38H68N10O14
- Purity
- >=99.5 HPLC
- Storage
- -20 °C, lyophilized
Research Notes
What is TB500?
TB500 is a synthetic research compound studied in laboratory settings. It has molecular formula C38H68N10O14, a molecular weight of 868.99 g/mol, CAS 885340-08-9. It is intended for in vitro research use only and is not for human or animal use.
What purity is AminoLine's TB500?
AminoLine supplies TB500 at >=99.5% purity, verified by third-party HPLC analysis. A certificate of analysis is available on request.
How is TB500 supplied?
TB500 is supplied as a lyophilized powder in sealed research-grade vials, stored -20 °C, lyophilized, intended for in vitro and laboratory research use only.